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Thyroid Disease Symptoms You Shouldn’t Ignore

By
Karabo Makodi
Published: 29 September 2025,
6 Min Read
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Thyroid Disease Symptoms You Shouldn’t Ignore
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Thyroid disorders are far more common than many South Africans realise. According to the South African Journal of Endocrinology, as much as 1 in 10 people could have an undiagnosed thyroid condition.

Contents
  • What Is the Thyroid and Why Is It Important?
  • Why Thyroid Disease Often Goes Undetected
  • Common Hypothyroidism Symptoms
  • Common Hyperthyroidism Symptoms
  • Watch for Subtle Early Signs
  • Don’t Dismiss Neck Swelling or Lumps
  • The Link Between Mood and Thyroid Health
  • Thyroid Disease in South Africa: The Local Picture
  • When to See a Doctor
  • How Thyroid Conditions Are Treated
  • Trust Your Symptoms

Because symptoms can be subtle, many brush them off as stress or ageing. However, recognising thyroid disease symptoms early can help prevent long-term complications.

What Is the Thyroid and Why Is It Important?

image 255
Image: Indus Health Plus

The thyroid is a small, butterfly-shaped gland located in your neck. It produces hormones that regulate your metabolism, energy levels, heart rate, and more. When the thyroid is underactive (hypothyroidism) or overactive (hyperthyroidism), it affects almost every part of your body.

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Why Thyroid Disease Often Goes Undetected

Thyroid symptoms often mimic other conditions like depression, anxiety, or menopause. As a result, many people go years without a proper diagnosis. A 2023 article in Frontiers in Endocrinology noted that no single symptom can definitively diagnose thyroid dysfunction.

“You should consult a healthcare professional if symptoms persist longer than a few weeks,” says Dr Sarah Iyer, endocrinologist at MD Anderson Cancer Centre.

Common Hypothyroidism Symptoms

Hypothyroidism, or an underactive thyroid, slows down your body processes. Common symptoms include:

  • Persistent fatigue or sluggishness
  • Unexplained weight gain
  • Feeling cold all the time
  • Dry skin and brittle nails
  • Constipation
  • Depression or low mood
  • Slow heart rate
  • Brain fog or memory issues

In South Africa, hypothyroidism is more prevalent in women over 35. According to SEMDSA, women are nearly 10 times more likely to be affected than men.

Common Hyperthyroidism Symptoms

Hyperthyroidism occurs when your thyroid is overactive. It speeds up your metabolism, sometimes dangerously. Symptoms to watch for include:

  • Rapid heartbeat or palpitations
  • Weight loss without trying
  • Nervousness, anxiety or irritability
  • Heat intolerance or excessive sweating
  • Increased appetite
  • Tremors or shaky hands
  • Trouble sleeping
  • Frequent bowel movements

Left untreated, hyperthyroidism can lead to heart problems, osteoporosis, and in severe cases, thyroid storm – a life-threatening condition.

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Watch for Subtle Early Signs

Some thyroid disease symptoms appear gradually. For example, thinning hair or eyebrows might be the first clue. Similarly, menstrual changes or difficulty concentrating may go unnoticed until they worsen.

A National Geographic article emphasised that over 60% of thyroid disorders remain undiagnosed. That’s why it’s crucial to pay attention to ongoing or unexplained symptoms.

Don’t Dismiss Neck Swelling or Lumps

A visible swelling in the neck, often called a goitre, is a key sign of thyroid disease. It may indicate a nodule or enlargement of the gland. While most thyroid nodules are benign, some can be cancerous.

According to CANSA, thyroid cancer accounts for 1.34% of all female cancers in South Africa. If you notice swelling, hoarseness, or difficulty swallowing, see a doctor immediately.

The Link Between Mood and Thyroid Health

Thyroid hormones play a major role in brain chemistry. Both hyperthyroidism and hypothyroidism can trigger mood disturbances.

  • Hypothyroidism may cause depression or apathy
  • Hyperthyroidism often leads to anxiety, irritability or panic attacks

A 2024 study in Time Health highlights unusual symptoms like sudden personality changes or emotional instability as potential red flags.

Thyroid Disease in South Africa: The Local Picture

Thyroid disorders in South Africa are often underreported. Cultural stigma and limited access to endocrinologists contribute to delayed diagnosis. The Wits University thyroid study from Chris Hani Baragwanath Hospital found diagnostic disparities in public healthcare.

Some areas in Gauteng also show higher rates of goitre due to past iodine deficiency, although this is improving with iodised salt interventions.

When to See a Doctor

See your GP or endocrinologist if you notice:

  • A family history of thyroid disease
  • Ongoing fatigue or weight changes
  • Mood swings without clear cause
  • Swelling in your neck
  • Changes in heart rate or skin condition

A simple blood test (TSH, T3, T4) can screen for thyroid imbalances. Early treatment can drastically improve quality of life.

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How Thyroid Conditions Are Treated

  • Hypothyroidism is treated with daily hormone replacement therapy (usually levothyroxine)
  • Hyperthyroidism may require medication, radioactive iodine therapy or surgery

Lifestyle adjustments, including stress management and balanced nutrition, can also support thyroid function. South Africans can access subsidised treatment through public hospitals or medical aid schemes.

Trust Your Symptoms

Many people ignore early signs, attributing them to stress, ageing or burnout. However, thyroid disease symptoms should not be taken lightly.

If you suspect something is wrong, don’t wait. Speak to a healthcare provider, get tested, and take action. Early diagnosis and treatment can prevent long-term damage to your heart, bones, and mental health.

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